Martina U Muckenthaler Selected Research

type 4 Hemochromatosis

1/2020	Mild Attenuation of the Pulmonary Inflammatory Response in a Mouse Model of Hereditary Hemochromatosis Type 4.
1/2020	Disruption of the hepcidin/ferroportin regulatory circuitry causes low axial bone mass in mice.
3/2019	Air-blood barrier thickening and alterations of alveolar epithelial type 2 cells in mouse lungs with disrupted hepcidin/ferroportin regulatory system.
6/2017	Disruption of the Hepcidin/Ferroportin Regulatory System Causes Pulmonary Iron Overload and Restrictive Lung Disease.
8/2014	Resistance of ferroportin to hepcidin binding causes exocrine pancreatic failure and fatal iron overload.

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Martina U Muckenthaler Research Topics

Disease

37	Iron Overload 01/2022 - 09/2004
26	Inflammation (Inflammations) 10/2022 - 05/2004
24	Hemochromatosis (Bronze Diabetes) 01/2022 - 05/2004
22	Iron Deficiencies 10/2022 - 08/2006
20	Anemia 10/2022 - 05/2004
12	Neoplasms (Cancer) 10/2022 - 05/2007
10	Infections 12/2021 - 05/2004
9	Hypoxia (Hypoxemia) 01/2017 - 01/2007
8	Precursor Cell Lymphoblastic Leukemia-Lymphoma (Acute Lymphoblastic Leukemia) 01/2020 - 01/2014
8	Precursor T-Cell Lymphoblastic Leukemia-Lymphoma (T-ALL) 01/2020 - 08/2006
6	Thalassemia 10/2021 - 10/2009
5	Hepatocellular Carcinoma (Hepatoma) 01/2022 - 05/2008
5	Leukemia 01/2020 - 05/2011
5	type 4 Hemochromatosis 01/2020 - 08/2014
4	Heart Failure 01/2022 - 12/2008
4	Iron-Refractory Iron Deficiency Anemia 12/2021 - 10/2009
3	Chronic Disease (Chronic Diseases) 12/2021 - 10/2012
3	Atherosclerosis 01/2020 - 01/2009
3	Lung Diseases (Lung Disease) 01/2020 - 06/2017
3	Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung) 01/2019 - 03/2016
3	Cataract (Cataracts) 04/2015 - 04/2010
3	Residual Neoplasm 01/2014 - 08/2006
2	Salmonella Infections (Salmonellosis) 12/2021 - 05/2013
2	Iron-Deficiency Anemia (Anemia, Iron Deficiency) 11/2021 - 05/2008
2	Hemorrhage 11/2021 - 12/2015
2	COVID-19 09/2021 - 12/2020
2	Hemolysis 01/2021 - 01/2016
2	Pneumonia (Pneumonitis) 01/2020 - 01/2012
2	Respiratory Tract Diseases (Respiratory Tract Disease) 03/2019 - 01/2019
2	Squamous Cell Carcinoma (Epidermoid Carcinoma) 01/2019 - 03/2016
2	Adenocarcinoma of Lung 01/2019 - 03/2016
2	Lung Neoplasms (Lung Cancer) 01/2019 - 03/2016
2	Neurodegenerative Diseases (Neurodegenerative Disease) 07/2017 - 04/2004
2	Acute-Phase Reaction 04/2015 - 05/2004
2	Body Weight (Weight, Body) 08/2014 - 03/2013
2	Hypochromic Anemia (Chlorosis) 06/2013 - 01/2006
2	Polycythemia (Erythrocytosis) 04/2013 - 10/2007
2	Alzheimer Disease (Alzheimer's Disease) 01/2012 - 01/2009
1	Breast Neoplasms (Breast Cancer) 10/2022
1	Liver Cirrhosis (Hepatic Cirrhosis) 01/2022
1	Arthritis (Polyarthritis) 01/2022
1	Meconium Ileus 01/2022
1	Hypertension (High Blood Pressure) 01/2022
1	Cystic Fibrosis (Mucoviscidosis) 01/2022
1	Acquired Immunodeficiency Syndrome (AIDS) 12/2021
1	Pulmonary Arterial Hypertension 11/2021
1	Deficiency Diseases (Deficiency Disease) 10/2021
1	Liver Diseases (Liver Disease) 10/2021
1	Communicable Diseases (Infectious Diseases) 09/2021
1	Type 1 Diabetes Mellitus (Autoimmune Diabetes) 06/2021
1	Obesity 01/2021

Drug/Important Bio-Agent (IBA)

83	IronIBA 10/2022 - 04/2004
38	HepcidinsIBA 10/2022 - 09/2004
14	Proteins (Proteins, Gene)FDA Link 01/2021 - 07/2008
12	Messenger RNA (mRNA)IBA 01/2020 - 09/2004
10	Ferritins (Ferritin)IBA 01/2022 - 04/2010
8	Hormones (Hormone)IBA 10/2021 - 05/2008
6	metal transporting protein 1 (ferroportin)IBA 03/2019 - 08/2013
6	Transferrin Receptors (Transferrin Receptor)IBA 01/2019 - 05/2004
6	MicroRNAs (MicroRNA)IBA 10/2014 - 05/2007
5	Interleukin-6 (Interleukin 6)IBA 10/2022 - 10/2012
5	Heme (Haem)IBA 01/2021 - 01/2012
5	Transferrin (beta 2 Transferrin)IBA 01/2020 - 04/2010
5	Biomarkers (Surrogate Marker)IBA 12/2017 - 01/2012
5	CytokinesIBA 10/2012 - 06/2005
4	Erythropoietin FDA Link 10/2022 - 03/2013
4	ApoferritinsIBA 04/2015 - 04/2010
4	ElementsIBA 04/2015 - 05/2007
3	Nitric Oxide (Nitrogen Monoxide)FDA Link 12/2021 - 05/2013
3	Hemoglobins (Hemoglobin)IBA 11/2021 - 04/2013
3	Bone Morphogenetic Proteins (Bone Morphogenetic Protein)IBA 10/2021 - 07/2008
3	RNA (Ribonucleic Acid)IBA 01/2020 - 03/2016
3	Prednisone (Sone)FDA LinkGeneric 01/2014 - 08/2006
3	LipopolysaccharidesIBA 09/2013 - 05/2004
2	Indicators and Reagents (Reagents)IBA 10/2022 - 11/2021
2	Dietary IronIBA 12/2021 - 01/2017
2	InterferonsIBA 12/2021 - 08/2012
2	ChromatinIBA 01/2020 - 01/2017
2	Small Interfering RNA (siRNA)IBA 12/2019 - 06/2018
2	Transcription Factors (Transcription Factor)IBA 01/2018 - 06/2017
2	Phosphotransferases (Kinase)IBA 01/2017 - 12/2008
2	Interleukin-7 (Interleukin 7)IBA 07/2014 - 05/2011
2	Cytokine Receptors (Cytokine Receptor)IBA 07/2014 - 05/2011
2	Cysteine (L-Cysteine)FDA Link 07/2014 - 05/2011
2	matriptase 2IBA 06/2013 - 07/2008
2	Serine Proteases (Serine Protease)IBA 03/2013 - 07/2008
2	CopperIBA 01/2012 - 01/2006
2	AntagomirsIBA 04/2011 - 12/2008
2	Iron-Regulatory Proteins (Iron-Responsive Element Binding Proteins)IBA 05/2007 - 06/2005
1	Deferasirox FDA Link 01/2022
1	MicellesIBA 10/2021
1	VaccinesIBA 09/2021
1	MicronutrientsIBA 09/2021
1	Intercellular Adhesion Molecule-1 (Intercellular Adhesion Molecule 1)IBA 01/2021
1	SelectinsIBA 01/2021
1	Glucose (Dextrose)FDA LinkGeneric 01/2021

Therapy/Procedure

7	Therapeutics 01/2021 - 04/2007
2	Drug Therapy (Chemotherapy) 11/2015 - 07/2009
1	PPA protocol 01/2022
1	Blood Transfusion (Blood Transfusions) 12/2021